UCC Researchers Part of EU Project to Tap Oceans for New Medicines

5th November 2021

UCC researchers Prof Alan Dobson and Dr David Clarke involved in EU project to tap oceans for new medicines

Prof Alan Dobson and Dr David Clarke are involved in EU project to tap oceans for new medicines

New antibiotics in the world’s oceans and the curative properties of marine animals like sponges will be explored in a European project involving researchers at University College Cork (UCC).

The EU has awarded a total of €7.5 million under its Horizon 2020 programme to the research into the largely unknown potential of the world’s oceans in protecting people, animals and crops from disease.

The Marine Biodiversity as Sustainable Resource of Disease-Suppressive Microbes and Bioprotectants for Aquaculture and Crop Diseases project, as it is officially known, has been given the name “Marbles”.

The research team will look specifically for new antibiotics and anti-fungals as well as microbes that can serve as “bio-protectants” in agriculture and aquaculture.

Synthetic chemicals currently used in pharmaceutical, agriculture and aquaculture have a devastating impact on marine life and this research is looking for sustainable solutions, according to the UCC research team.

The project will assess the potential of microorganisms derived from marine sponges, microalgae and fish for disease suppression.

They explain that “disease-suppressive” microorganisms will be drawn from "microbiomes", the complex collection of microorganisms that live in and around their marine hosts.

The world’s growing population and the current climate and biodiversity crises are driving the need to harness new compounds with pharmaceutical and nutritional applications sustainably, the UCC team says.

Prof Alan Dobson and Dr David Clarke from the UCC School of Microbiology and the Environmental Research Institute said that they were particularly excited about collaborating with the other 13 European partners from both academia and industry.

One project they hope to focus on involves isolating and genetically characterising disease suppressive microorganisms from the microbiome of Atlantic salmon.

These may then be generated into cocktails of microbial consortia, which could then be used either within fish feed as probiotics, or applied externally to boost the skin’s immune response in the salmon, they state.

This will improve disease control and overall fish health, and should decrease the dependency of using antibiotics in fish aquaculture systems while also reducing the potential spread of antimicrobial resistance in aquatic ecosystems, they state.

Published in Marine Science, Marine Wildlife

Published in Marine Science

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Lorna Siggins

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Lorna Siggins is a print and radio reporter, and a former Irish Times western correspondent. She is the author of Search and Rescue: True stories of Irish Air-Sea Rescues and the Loss of R116 (2022); Everest Callling (1994) on the first Irish Everest expedition; Mayday! Mayday! (2004); and Once Upon a Time in the West: the Corrib gas controversy (2010). She is also co-producer with Sarah Blake of the Doc on One "Miracle in Galway Bay" which recently won a Celtic Media Award

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